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Prof. Dr. Mukhlesur Rahman

Visiting Professor

BPharm (Hons), MPharm, PhD, Research Group Lead of Medicines Research Group Department of Bioscience , School Of Health, Sport And Bioscience

Mukhlesur Rahman completed his Bachelor of Pharmacy (Hons) and Master of Pharmacy with first class from the University of Dhaka. He completed PhD in Natural Product Chemistry from the University of Strathclyde with Commonwealth Scholarship and worked as a postdoctoral research fellow (over 3 years) at the School of Pharmacy, University of London (currently known as UCL School of Pharmacy). Dr Rahman has over 17 years of teaching experience in Higher Education Institutions (University of East London, Liverpool John Moores University and Rajshahi University). He also has three years of industrial experiences in pharmaceutical (Organon) and biotechnology (Novacta Biosystem). With his academic and industrial experiences, he designed and developed two brand new courses (BSc (Hons) Pharmaceutical Science and MSc Pharmaceutical) at UEL. Between 2012-2019, he served as Programme Leader of both BSc (Hons) and MSc Pharmaceutical Science courses. Over the years he was involved in curricula developments, validation and revalidation processes for these courses. He has led several new modules over the years. Dr Rahman is leading the Medicines Research Group at UEL and also leading the Health Sport and Bioscience seminar series. With significant research responsibility, he has established strong research collaboration with top UK universities and organizations including UCL, Strathclyde, Birkbeck, Kew Botanical Garden and Liverpool John Moores University. Outside the UK, he collaborates with several universities in India, Bangladesh, China, Nigeria and Ghana. Dr Rahman is currently serving as associate editor of Journal of Herbal Medicine, Frontiers in Pharmacology and topic editor in Frontiers in Pharmacology on the research topic Natural Products as Potential Therapeutics to Tackle Life-Threatening Infections: From Field to Market

Journal Articles

2022

  1. Shaik, A. B., Lagu, S. B., Yejella, R. P., Nissankararao, S., Bhandare, R. R., Golla, V. S., Lokesh, B. V. S., and Rahman, M. M. (2022) Antitubercular activity assessment of fluorinated chalcones, 2‐aminopyridine‐3‐carbonitrile and 2‐amino-4H-pyran‐3‐carbonitrile derivatives: In vitro, molecular docking and in-silico drug likeliness studies, PLOS One (in press)
  2. Saha, P., Rahman, F. I., Hussain, F., Rahman, S. M. A. and Rahman, M. M. (2021) Antimicrobial diterpenes:a systematic review on the recent development from natural sources, Frontiers in Pharmacology

2021

  1. Siddique, H., Pendry, B., Rashid, M. A. and Rahman, M. M., (2021) Medicinal plants used to treat infectious diseases in the central part and a northern district of Bangladesh - An ethnopharmacological perception, Journal of Herbal Medicine, 29, 100484.
  2. Al-Majmaie, S., Nahar, L., Rahman, M. M.,  Nath, S., Saha, P., Talukdar, A. D., Sharples, G. P. and Sarker, S. D. (2021) Anti-MRSA constituents from Ruta chalepensis (Rutaceae)grown in Iraq, and in Silico studies on two of most active compounds, chalepensin and 6-hydroxy-rutin 3',7-dimethyl ether, Molecules 26, 1114.
  3. Shaik, A. B., Bhandare, R. R., Nissankararao, S., Lokesh, B. V. S., Shahanaaz, S. and Rahman, M. M. (2021) Synthesis and biological screening of chloropyrazine conjugated benzothiazepine derivatives as potential antimicrobial, antitubercular and cytotoxic agents, Arabian Journal of Chemistry, 14(2), 102915.

2020

  1. Shaik, A. B., Bhandare, R. R., Nissankararao, S., Edis, Z., Tangirala, N. R., Shahanaaz, S. and Rahman, M. M. (2020) Design, facile synthesis and characterization of dichloro substituted chalcones and dihydropyrazole derivatives for their antifungal, antitubercular and antiproliferative activities, Molecules,  25(14), 3188.

2019

  1. Siddique, H., Pendry, B., and Rahman, M. M., (2019) Terpenes from Zingiber montanum and their screening against multi-drug resistant and methicillin resistant Staphylococcus aureus, Molecules, 24(3), 385.

2018

  1. Danquah, C. A., Kakagianni, E., Khondkar, P., Maitra, A., Rahman, M. M., Evangelopoulos, D., McHugh, T. D., Stapleton, P., Bhakta, S. and Gibbons, S. (2018) Analogues of disulfides from Allium stipitatum demonstrate potent anti-tubercular activities through drug efflux pump and biofilm inhibition, Scientific Reports 8, 1150.
  2. Rahman, M. M., Shiu, W. K. P., Malkinson, J. P., Gibbons, S. (2018) Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus, European Journal of Medicinal Chemistry 155, 255-262.
  3. Tareq, F. S., Hasan, C. M., Rahman, M. M., Hanafi, M. M. M., Spiteller, P. (2018) Anti-staphylococcal Calopins from fruiting bodies of Caloboletus radicans, Journal of Natural Products, 81 (2), 400–404.
  4. Nurunnabi, T., Nahar, L., Al-Makmaie, S., Rahman, S. M. M., Sohrab, M. H., Billah, M.M., Ismail, F.M.D., Rahman, M. M., Sharples, G, P. and Sarker, S.D. (2018) Anti-MRSA activity of oxysporone and xylitolfrom the endophytic fungus Pestalotia sp. growing on the Sundarbans mangrove plant Heritiera fomes, Phytotherapy Research, 32 (2), 348-352.

2016

  1. Mundy, L., Pendry, B. and Rahman, M. M. (2016) Antimicrobial resistance and synergy in herbal medicine, Journal of Herbal Medicine, 6(2), 53–58. https://doi.org/10.1016/j.hermed.2016.03.001

2015

  1. Rahman, M. M. and Gibbons, S. (2015) Antibacterial constituents of Neohyptis paniculata, Fitoterapia 105, 269-272. https://doi.org/10.1016/j.fitote.2015.07.012

2014

  1. Xia, H., Sun, L., Lou, H. and Rahman, M. M. (2014) Conversion of salvianolic acid B into salvianolic acid A in tissues of Radix Salviae Miltiorrhizae using high temperature, high pressure and high humidity, Phytomedicine 21(6), 906-11. https://doi.org/10.1016/j.phymed.2014.01.005

2013

  1. Shiu, W. K. P., Malkinson, J. P., Rahman, M. M., Curry, J., Stapleton, P., Gunaratnam, M., Neidle, S., Mushtaq, S., Warner, M., Livermore, D. M., Evangelopoulos, D., Basavannacharya, C., Bhakta, S., Schindler, B. D., Seo, S. M., Coleman, D., Kaatz, G. W., Gibbons, S. (2013) A new plant-derived antibacterial is an inhibitor of efflux pumps in Staphylococcus aureus, International Journal of Antimicrobial Agents 42 (6), 513-518. https://doi.org/10.1016/j.ijantimicag.2013.08.007

2012

  1. Shiu, W. K. P., Rahman, M. M., Curry, J., Stapleton, P., Zloh, M., Malkinson, J. P., Gibbons, S. (2012) Antibacterial acylphloroglucinols from Hypericum olympicum, Journal of Natural Products 75 (3), 336–343. https://doi.org/10.1021/np2003319
  2. oannou, E., Quesada, A., Rahman, M. M., Gibbons, S., Vagias, C. and Roussis, V. (2012) Structure and antibacterial activities of minor dolabellanes from the brown alga Dilophus spiralis, European Journal of Organic Chemistry 27, 5177-5186. https://doi.org/10.1002/ejoc.201200533

2011

  1. Garvey, M. I., Rahman, M. M., Gibbons, S. and Piddock, L. J. V. (2011) Medicinal plant extracts with efflux inhibitory activity against Gram negative bacteria, International Journal of Antimicrobial Agents 37 (2), 145-151. 
  2. Guzman, J. D., Wube, A., Evangelopoulos, D., Gupta, A., Hüfner, A., Basavannacharya, C., Rahman, M. M., Thomaschitz, C., Bauer, R., McHugh, T. D., Nobeli, I., Prieto, J. M., Gibbons, S. Bucar, F. and Sanjib Bhakta, S. (2011) Interaction of N-methyl-2-alkenyl-4-quinolones with ATP-dependent MurE ligase of Mycobacterium tuberculosis: antibacterial activity, molecular docking and inhibition kinetics, Journal of Antimicrobial Chemotherapy 66 (8), 1766–1772. 
  3. Ioannou, E., Quesada, A., Rahman, M. M., Gibbons, S., Vagias, C. and Roussis, V. (2011) Dolabellnes with antibacterial activity from the brown alga Dilophus spiralis, Journal of Natural Products 74 (2), 213-222.
  4. Delazar, A., Delnavazi, M. R., Nahar, L., Moghadam, S. B., Mojarab, M., Gupta, A., Williams, A. S., Rahman, M. M. and Sarker, S. D. (2011) Lavandulifolioside B: a new phenylethanoid glycoside from the aerial parts of Stachys lavandulifolia Vahl. Natural Product Research 25 (1), 8–16.
  5. Begum, R., Kaisar, M. A., Rahman, M. S., Chowdhury, A. M. S., Rahman, M. M., Hasan, C. M., and Rashid, M. A. (2011) Clausenolide-1-methyl ether from Clausena heptaphylla W & A The Latin American and Caribbean Bulletin of Medicinal and Aromatic Plants (BLACPMA) 10 (2): 136 -138.





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